Child, Adolescent, and Geriatric Psychiatry

Mental health across the lifespan is influenced by neurodevelopmental and neurodegenerative processes. In children and adolescents, neurodevelopmental disorders such as autism spectrum conditions and attention deficit hyperactivity disorder are linked to alterations in cortical connectivity, neurotransmitter imbalances, and genetic susceptibility. Early-life stress can modify gene expression through epigenetic mechanisms, affecting vulnerability to psychiatric disorders. Adolescence involves critical brain maturation, particularly in the prefrontal cortex, influencing emotional regulation and risk-taking behavior. In older adults, cognitive decline, dementia, and late-onset mood disorders are associated with neuronal loss, synaptic dysfunction, and vascular pathology. Neuroinflammation, oxidative stress, and amyloid accumulation contribute to neurodegenerative processes. Pharmacological strategies, cognitive interventions, and neuroprotective therapies aim to modulate these biological pathways to maintain cognitive function and emotional stability throughout life.

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